Surface plasmon resonance

Surface plasmon resonance Imaging ushers in label free microarray analysis
Posted on March 6, 2008 by Albin Paul

Surface plasmon resonance (SPR) reflectivity measurements are surface-sensitive, spectroscopic methods that can be used to characterize the thickness and/or index of refraction of ultrathin organic and biopolymer films at gold, silver surfaces.

The probes can be proteins, peptides, nucleic acids, sugars, membranes, or any other molecule. GWC Technologies is one such company that offers the services in this field

SPR imaging detects the presence of a biopolymer on a chemically modified gold surface by the change in the local index of refraction that occurs upon adsorption.

Research Papers are on , University of California, Irvine page and also at

UC Davis Biophotonics center web page


Filed under: Next Generation of DNA and RNA Microarrays, microarray